Full-scale industrial phage trial concentrating on Salmonella on pork carcass – Swine abstracts


Phages have been prompt as promising biocontrol brokers in meals, however trials demonstrating the effectivity of phage therapy underneath industrial settings are lacking. Right here we carried out a full-scale industrial trial to guage the efficacy of a business phage product to cut back the prevalence of naturally occurring Salmonella on pork carcasses. A complete of 134 carcasses from probably Salmonella-positive finisher herds have been chosen to be examined on the slaughterhouse based mostly on the extent of antibodies within the blood. Throughout 5 consecutive runs, carcasses have been directed right into a cabin spraying phages, leading to a dosage of roughly 2 × 107 phages per cm2 carcass floor. To guage the presence of Salmonella, a predefined space of 1 half of the carcass was swabbed earlier than phage software and the opposite half 15 min after. A complete of 268 samples have been analysed by Actual-Time PCR.

Below these optimized check circumstances, 14 carcasses have been discovered constructive earlier than phage software, whereas solely 3 carcasses have been constructive after.

This work exhibits that phage software permits to attain approximatively 79% discount of Salmonella-positive carcasses and demonstrates that implementation of phage software in industrial settings can be utilized as an extra technique to manage foodborne pathogens.

Volpi M, Gambino M, Kirkeby Ok, Elsser-Gravesen A, Brøndsted L.
Full-scale industrial phage trial concentrating on Salmonella on pork carcasses. Meals Microbiology. 2023; 112: 104240. https://doi.org/10.1016/j.fm.2023.104240.


Please enter your comment!
Please enter your name here