An interview with founder & CEO of Axitan – Dr. Kane Miller

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Axitan is a brand new biotech firm that develops non-antibiotic feed additive options


calendar icon 12 September 2023

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3 minute learn

Editor’s notice: Final week I caught up with the founder and CEO of Axitan, Dr. Kane Miller, by way of Zoom. His firm is targeted on growing a library of antimicrobial enzymes, referred to as endolysins, that selectively destroy economically essential micro organism in animal agriculture. Their first industrial product – referred to as FORC3® – addresses Clostridium perfringens in poultry. Take a look at the interview beneath.

Who’s Axitan?

At its core, Axitan is a biotech firm that was established to develop a non-antibiotic based mostly feed additive resolution to deal with problematic micro organism traditionally managed by antibiotics in animal feed. Not surprisingly, our core administration group – myself, Dr Wei Lee (COO) and Dr Francisco Navarro (CSO) – are all scientists from main UK and US establishments. We’re then supported by a extremely skilled Board from the US agricultural sector and are delighted to have Clint Severson as a enterprise advisor and shareholder. Clint is maybe greatest recognized for reworking Abaxis and exiting it to Zoetis for circa $1.9b in 2018.

What’s what you are promoting focus?

Our enterprise focus is the event of endolysin based mostly options for:

  1. concentrating on and destroying micro organism that influence livestock farming
  2. bettering the effectivity of livestock manufacturing

To clarify, an endolysin an antimicrobial enzyme that particularly binds to after which cuts the cell wall (the peptidoglycan layer) of the focused micro organism, inflicting it to burst.

In order a biotech firm, we’re within the enterprise of figuring out the simplest endolysins for concentrating on any given pathogen and, in parallel, formulating them into merchandise of economic relevance.

What particular issues do you clear up for poultry producers/trade?

Inside the poultry trade, our first product has been developed to deal with two very common challenges integrators inform us they face:

  1. managing Clostridium perfringens in a NAE context extra scientifically and sustainably
  2. the fixed want to enhance efficiency KPI’s similar to feed conversion and every day weight acquire, each in “No Antibiotics Ever” and “No Antibiotics Essential to Human Drugs” settings

Species focused/forms of product(s)?

Our first product is known as FORC3. It’s a GRAS-affirmed feed additive particularly for poultry and is often included into starter and grower feed. Inclusion ranges usually run on the 1lb per ton stage, it being combined into the feed on the feed mill.

What makes what you are promoting/merchandise distinctive?

With out eager to overstate it, we’re growing a brand new sort of feed additive that may assist form the way forward for the animal feed additive trade internationally because it transitions away from antibiotics and ionophores.

Dr. Kane Miller obtained an Engineering Doctorate (EngD) in Biochemical Engineering from College Faculty London (UCL). He earned his BSc in Mathematical Physics on the College of Nottingham, adopted by a Grasp’s diploma in Biochemical Engineering at UCL. Kane’s doctoral research targeted on algal manufacturing methods. After graduating, he spent a 12 months as a Postdoctoral Analysis Affiliate the place he investigated the industrial functions of algal biotechnology. It was throughout this time that the idea of making use of algal biotechnology to animal agriculture got here into focus. Because the founding father of Axitan, he’s carefully concerned in all features of the enterprise. While his position has advanced, from a bioprocess engineering focus at Axitan’s conception, he nonetheless is actively concerned within the scientific, manufacturing, and regulatory decision-making course of. Kane oversees Axitan’s technique and its execution, along with offering steerage, administration and motivation to the remainder of the group. He additionally authored and co-authored each of Axitan’s profitable Innovate UK grant proposals and has spearheaded Axitan’s fundraising actions.



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